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Sku: P111461-50 μl
Categories: Primary Antibodies

Specification

Full name POLH rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
Swissprot No Q9Y253
Gene Accession BC015742
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or POLH antigen-treated (Neutralization experiment) using P111461(POLH Antibody) at dilution 1/45
WB Positive control P111461-WB-1-P
WB Recommended dilution 78 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human tonsil
IHC Recommed dilution Recommended dilution: 50-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P111461-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or POLH antigen-treated (Neutralization experiment) using P111461(POLH Antibody) at dilution 1/45

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