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Full name | POLH rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. |
Swissprot No | Q9Y253 |
Gene Accession | BC015742 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or POLH antigen-treated (Neutralization experiment) using P111461(POLH Antibody) at dilution 1/45 |
WB Positive control | P111461-WB-1-P |
WB Recommended dilution | 78 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 50-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P111461-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or POLH antigen-treated (Neutralization experiment) using P111461(POLH Antibody) at dilution 1/45
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