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Sku: 5919-5
Categories: Chemical

Description

PI 3065 is a potent and selective PI 3-kinase p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM). Exhibits >100-fold selectivity over p100α, p100γ and p100β isoforms (IC50 values are 600, 910, >10,000 nM, respectively). Attenuates 4TI tumor growth and metastasis in vivo.

For research use only. We do not sell to patients.

 

Specification

Chemical Name 6-[4-(Cyclopropylmethyl)-1-piperazinyl]methyl[3,2-d]pyrimidine
Purity ≥98%
M.Wt 506.64
Formula C27H31FN6OS
Solubility Soluble to 20 mM in DMSO
Storage Store at -20°C
CAS No. 955977-50-1

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