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PI 3065 is a potent and selective PI 3-kinase p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM). Exhibits >100-fold selectivity over p100α, p100γ and p100β isoforms (IC50 values are 600, 910, >10,000 nM, respectively). Attenuates 4TI tumor growth and metastasis in vivo.
For research use only. We do not sell to patients.
Chemical Name | 6-[4-(Cyclopropylmethyl)-1-piperazinyl]methyl[3,2-d]pyrimidine |
Purity | ≥98% |
M.Wt | 506.64 |
Formula | C27H31FN6OS |
Solubility | Soluble to 20 mM in DMSO |
Storage | Store at -20°C |
CAS No. | 955977-50-1 |
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