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Specification
| Full name | ORC2 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. |
| Swissprot No | Q13416 |
| Gene Accession | BC014834 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or ORC2 antigen-treated (Neutralization experiment) using P114292(ORC2 Antibody) at dilution 1/80 |
| WB Positive control | P114292-WB-1-P |
| WB Recommended dilution | 66 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus |
| IHC positive control | Positive control: Human liver cancer |
| IHC Recommed dilution | Recommended dilution: 50-100 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P114292-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or ORC2 antigen-treated (Neutralization experiment) using P114292(ORC2 Antibody) at dilution 1/80
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We also provide express shippping for time-sensitive deliveries.
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