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Description
Olpasiran is a first-in-class, siRNA designed to inhibit LPA mRNA translation in hepatocytes and thereby reduce plasma Lipoprotein(a) or Lp(a) concentration.
Product information
Targets: Lipoprotein(a); Lipoprotein
Synonym: Olpasiran
Chemical Name/IUPAC:
Technical Data
| Product Name | Olpasiran |
| Chemical Formula | (Duplex): C490H652F11N164O306P41S7 |
| Molecular Weight | 15438.70 |
| CAS# | 2225856-03-9 |
| Appearance | Solid powder |
| Purity | > 99% by HPLC |
| Solubility | Soluble in DMSO |
| Storage | Room temperature for months, or -20ºC for 3 years |
References
https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8M4GC1EOB4
https://drugs.ncats.io/substance/8M4GC1EOB4
https://pubchem.ncbi.nlm.nih.gov/substance/472420032
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