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Sku: P113948-50 μl
Categories: Primary Antibodies

Specification

Full name NR1H2 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).
Swissprot No P55055
Gene Accession BC007790
WB Predicted band size
WB Positive control P113948-WB-1-P
WB Recommended dilution 51 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 100-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P113948-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or NR1H2 antigen-treated (Neutralization experiment) using P113948(NR1H2 Antibody) at dilution 1/120

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