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Full name | NR1H2 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]). |
Swissprot No | P55055 |
Gene Accession | BC007790 |
WB Predicted band size | |
WB Positive control | P113948-WB-1-P |
WB Recommended dilution | 51 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human thyroid cancer |
IHC Recommed dilution | Recommended dilution: 100-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P113948-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or NR1H2 antigen-treated (Neutralization experiment) using P113948(NR1H2 Antibody) at dilution 1/120
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