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Sku: P109228-50 μl
Categories: Primary Antibodies

Specification

Full name NELFA rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Swissprot No Q9H3P2
Gene Accession BC002764
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or NELFA antigen-treated (Neutralization experiment) using P109228(NELFA Antibody) at dilution 1/100
WB Positive control P109228-WB-1-P
WB Recommended dilution 57 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 100-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P109228-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or NELFA antigen-treated (Neutralization experiment) using P109228(NELFA Antibody) at dilution 1/100

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