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Sku: P101030-50 μl
Categories: Primary Antibodies

Specification

Full name NECTIN4 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Swissprot No Q96NY8
Gene Accession BC010423
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissue or NECTIN4 antigen-treated (Neutralization experiment) using P101030(NECTIN4 Antibody) at dilution 1/70
WB Positive control P101030-WB-1-P
WB Recommended dilution 55 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P101030-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or NECTIN4 antigen-treated (Neutralization experiment) using P101030(NECTIN4 Antibody) at dilution 1/70

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