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Sku: P110171-50 μl

Specification

Full name NCR1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Natural killer (NK) cells mediate MHC nonrestricted cytotoxicity. There are many candidate molecules for NK cell recognition structures, including inhibiting and activating receptors. Using a monoclonal antibody capable of triggering NK-mediated lysis, Sivori et al. (1997) identified a cell surface molecule of 46 kD that they termed p46. The molecule lacks N-linked sugars and is expressed on resting and activated NK cells but not on T cells or B cells. In addition to lytic activity, monoclonal antibody-mediated crosslinking induces intracellular calcium increases and cytokine production.
Swissprot No O76036
Gene Accession NP_001138929
WB Predicted band size
WB Positive control P110171-WB-1-P
WB Recommended dilution 34 kDa
IHC predicted cell location Predicted cell location: Cell membrane
IHC positive control Positive control: Human liver cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P110171-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or NCR1 antigen-treated (Neutralization experiment) using P110171(NCR1 Antibody) at dilution 1/50

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