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Full name | NCR1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Natural killer (NK) cells mediate MHC nonrestricted cytotoxicity. There are many candidate molecules for NK cell recognition structures, including inhibiting and activating receptors. Using a monoclonal antibody capable of triggering NK-mediated lysis, Sivori et al. (1997) identified a cell surface molecule of 46 kD that they termed p46. The molecule lacks N-linked sugars and is expressed on resting and activated NK cells but not on T cells or B cells. In addition to lytic activity, monoclonal antibody-mediated crosslinking induces intracellular calcium increases and cytokine production. |
Swissprot No | O76036 |
Gene Accession | NP_001138929 |
WB Predicted band size | |
WB Positive control | P110171-WB-1-P |
WB Recommended dilution | 34 kDa |
IHC predicted cell location | Predicted cell location: Cell membrane |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P110171-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or NCR1 antigen-treated (Neutralization experiment) using P110171(NCR1 Antibody) at dilution 1/50
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