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Full name | MMP13 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |
Swissprot No | P45452 |
Gene Accession | BC067522 |
WB Predicted band size | |
WB Positive control | P100059-WB-1-P |
WB Recommended dilution | 54 kDa |
IHC predicted cell location | Predicted cell location: Secreted |
IHC positive control | Positive control: Human breast cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P100059-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or MMP13 antigen-treated (Neutralization experiment) using P100059(MMP13 Antibody) at dilution 1/55
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