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Full name | MICA rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
Swissprot No | Q29983 |
Gene Accession | BC016929 |
WB Predicted band size | |
WB Positive control | P113487-WB-1-P |
WB Recommended dilution | 43 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human cervical cancer |
IHC Recommed dilution | Recommended dilution: 100-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P113487-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or MICA antigen-treated (Neutralization experiment) using P113487(MICA Antibody) at dilution 1/110
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