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Specification
| Full name | MDM2 (phospho-Ser166) rabbit monoclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit monoclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit monoclonal |
| Target Background | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013] |
| Swissprot No | Q00987 |
| Gene Accession | 4193 |
| WB Predicted band size | |
| WB Positive control | P290921-WB-1-P |
| WB Recommended dilution | 55 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus |
| IHC positive control | Positive control: Human colon cancer |
| IHC Recommed dilution | Recommended dilution: 50-100 |
Storage
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
WB PIC Description
P290921-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P290921(MDM2 (phospho-Ser166) Antibody) at dilution 1/50
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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