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Specification
| Full name | MCM6 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. |
| Swissprot No | Q14566 |
| Gene Accession | BC032374 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or MCM6 antigen-treated (Neutralization experiment) using P100335(MCM6 Antibody) at dilution 1/60 |
| WB Positive control | P100335-WB-1-P |
| WB Recommended dilution | 93 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus |
| IHC positive control | Positive control: Human esophagus cancer |
| IHC Recommed dilution | Recommended dilution: 100-300 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P100335-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or MCM6 antigen-treated (Neutralization experiment) using P100335(MCM6 Antibody) at dilution 1/60
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We also provide express shippping for time-sensitive deliveries.
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