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Full name | MCM2 (phospho-Ser27) rabbit monoclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit monoclonal |
Applications | WB, IHC, IF |
Host | Rabbit |
Clone type | rabbit monoclonal |
Target Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] |
Swissprot No | P49736 |
Gene Accession | 4171 |
WB Predicted band size | |
WB Positive control | P290911-WB-1-P |
WB Recommended dilution | 102 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
P290911-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using P290911(MCM2 (phospho-Ser27) Antibody) at dilution 1/50
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