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Full name | MASP1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants. |
Swissprot No | P48740 |
Gene Accession | BC106945 |
WB Predicted band size | |
WB Positive control | P104748-WB-1-P |
WB Recommended dilution | 79 kDa |
IHC predicted cell location | Predicted cell location: Secreted |
IHC positive control | Positive control: Human breast cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P104748-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or MASP1 antigen-treated (Neutralization experiment) using P104748(MASP1 Antibody) at dilution 1/80
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