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Specification
| Full name | MAPK1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
| Swissprot No | P28482 |
| Gene Accession | NP_002736 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or MAPK1 antigen-treated (Neutralization experiment) using P114828(MAPK1 Antibody) at dilution 1/50 |
| WB Positive control | P114828-WB-1-P |
| WB Recommended dilution | 41 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human cervical cancer |
| IHC Recommed dilution | Recommended dilution: 50-100 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P114828-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or MAPK1 antigen-treated (Neutralization experiment) using P114828(MAPK1 Antibody) at dilution 1/50
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