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Specification
| Full name | MAPK1/MAPK3 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
| Swissprot No | P28482/P27361 |
| Gene Accession | NP_002736/NP_002737 |
| WB Predicted band size | |
| WB Positive control | P102161-WB-1-P |
| WB Recommended dilution | 41 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human liver cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P102161-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or MAPK1/MAPK3 antigen-treated (Neutralization experiment) using P102161(MAPK1/MAPK3 Antibody) at dilution 1/50
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We also provide express shippping for time-sensitive deliveries.
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