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Full name | MAP3K7 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Swissprot No | O43318 |
Gene Accession | BC017715 |
WB Predicted band size | |
WB Positive control | P108924-WB-1-P |
WB Recommended dilution | 67 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 200-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P108924-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or MAP3K7 antigen-treated (Neutralization experiment) using P108924(MAP3K7 Antibody) at dilution 1/150
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