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Specification
| Full name | LRP1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. |
| Swissprot No | Q07954 |
| Gene Accession | NP_002323 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or LRP1 antigen-treated (Neutralization experiment) using P113982(LRP1 Antibody) at dilution 1/50 |
| WB Positive control | P113982-WB-1-P |
| WB Recommended dilution | 505 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human colorectal cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P113982-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or LRP1 antigen-treated (Neutralization experiment) using P113982(LRP1 Antibody) at dilution 1/50
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We also provide express shippping for time-sensitive deliveries.
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