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Sku: P112627-50 μl

Specification

Full name LFNG rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3.
Swissprot No Q8NES3
Gene Accession BC014851
WB Predicted band size 42 kDa
WB Positive control
WB Recommended dilution 500-2000
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human tonsil
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P112627-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or LFNG antigen-treated (Neutralization experiment) using P112627(LFNG Antibody) at dilution 1/60

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