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Full name | LFNG rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. |
Swissprot No | Q8NES3 |
Gene Accession | BC014851 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or LFNG antigen-treated (Neutralization experiment) using P112627(LFNG Antibody) at dilution 1/60 |
WB Positive control | P112627-WB-1-P |
WB Recommended dilution | 42 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P112627-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or LFNG antigen-treated (Neutralization experiment) using P112627(LFNG Antibody) at dilution 1/60
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