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Specification
| Full name | KCNQ4 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. |
| Swissprot No | P56696 |
| Gene Accession | NP_004691 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human brain tissue or KCNQ4 antigen-treated (Neutralization experiment) using P102835(KCNQ4 Antibody) at dilution 1/40 |
| WB Positive control | P102835-WB-1-P |
| WB Recommended dilution | 77 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human liver cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P102835-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or KCNQ4 antigen-treated (Neutralization experiment) using P102835(KCNQ4 Antibody) at dilution 1/40
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