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Sku: P114840-50 μl

Specification

Full name IFNA2 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach.
Swissprot No P01563
Gene Accession
WB Predicted band size
WB Positive control P114840-WB-1-P
WB Recommended dilution 22 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P114840-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or IFNA2 antigen-treated (Neutralization experiment) using P114840(IFNA2 Antibody) at dilution 1/50

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