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Human Angiotensinogen; SERPINA8; Serpin Peptidase Inhibitor, Clade A, Member 8; Alpha-1 Antiproteinase, Antitrypsin; Serpin A8; Serine (Or Cysteine) Proteinase Inhibitor; Fetal-Liver Predominant Transporter 1; Pre-Angiotensinogen; Angiotensin II; Angiotensin I; HFLT1; ANHU
$160.00
Sku: RP967-10UG
Bcakground
The human AGT is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Specifications
| Synonyms | Angiotensinogen; SerpinA8AF; AGT; SERPINA8. |
| Accession # | P01019. |
| Source | Human embryonic kidney cell, HEK293-derived human Angitensinogen protein, Met 1-Ala 485. |
| Predicted Moleucular weight | 49.8 kDa |
Components and Storage
| Formulation | Solution protein |
| Dissolved in sterile PBS buer . | |
| This solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening. | |
| Storage and Stability | Avoid repeated freeze-thaw cycles. |
| It is recommended that the protein be aliquoted for optimal storage. | |
| 12 months from date of receipt, -20 to -70 as supplied. | |
| Shipping | Shipping with dry ice |
Quality
| Purity | ≥95%, determined by SDS-PAGE |
| Endotoxin Stability | ＜0.01 EU per 1 µg of the protein by the LAL method. |
| Shipping | Testing in progress. |
SDS-PAGE
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
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