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Specification
| Full name | HLA-DOB rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
| Swissprot No | P13765 |
| Gene Accession | NP_002111 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or HLA-DOB antigen-treated (Neutralization experiment) using P111840(HLA-DOB Antibody) at dilution 1/40 |
| WB Positive control | P111840-WB-1-P |
| WB Recommended dilution | 31 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human tonsil |
| IHC Recommed dilution | Recommended dilution: 30-150 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P111840-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or HLA-DOB antigen-treated (Neutralization experiment) using P111840(HLA-DOB Antibody) at dilution 1/40
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Most orders are filled and shipped within 2-3 business days from the time they are received.
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We also provide express shippping for time-sensitive deliveries.
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