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Specification
| Full name | HLA-DMB rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
| Swissprot No | P28068 |
| Gene Accession | BC027175 |
| WB Predicted band size | |
| WB Positive control | P103820-WB-1-P |
| WB Recommended dilution | 29 kDa |
| IHC predicted cell location | Predicted cell location: Cell membrane |
| IHC positive control | Positive control: Human prostate cancer |
| IHC Recommed dilution | Recommended dilution: 30-150 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P103820-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or HLA-DMB antigen-treated (Neutralization experiment) using P103820(HLA-DMB Antibody) at dilution 1/40
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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