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Specification
| Full name | HIF1A rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| Swissprot No | Q16665 |
| Gene Accession | BC012527 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or HIF1A antigen-treated (Neutralization experiment) using P114452(HIF1A Antibody) at dilution 1/120 |
| WB Positive control | P114452-WB-1-P |
| WB Recommended dilution | 93 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human cervical cancer |
| IHC Recommed dilution | Recommended dilution: 100-300 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P114452-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or HIF1A antigen-treated (Neutralization experiment) using P114452(HIF1A Antibody) at dilution 1/120
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We also provide express shippping for time-sensitive deliveries.
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