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Full name | HEXA rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
Swissprot No | P06865 |
Gene Accession | BC018927 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or HEXA antigen-treated (Neutralization experiment) using P114519(HEXA Antibody) at dilution 1/100 |
WB Positive control | P114519-WB-1-P |
WB Recommended dilution | 61 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 100-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P114519-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or HEXA antigen-treated (Neutralization experiment) using P114519(HEXA Antibody) at dilution 1/100
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