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Sku: P105655-50 μl
Categories: Primary Antibodies

Specification

Full name GSTM4 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.
Swissprot No Q03013
Gene Accession BC015513
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or GSTM4 antigen-treated (Neutralization experiment) using P105655(GSTM4 Antibody) at dilution 1/80
WB Positive control P105655-WB-1-P
WB Recommended dilution 26 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human gastric cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P105655-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or GSTM4 antigen-treated (Neutralization experiment) using P105655(GSTM4 Antibody) at dilution 1/80

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