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Specification
| Full name | GSTM4 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. |
| Swissprot No | Q03013 |
| Gene Accession | BC015513 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or GSTM4 antigen-treated (Neutralization experiment) using P105655(GSTM4 Antibody) at dilution 1/80 |
| WB Positive control | P105655-WB-1-P |
| WB Recommended dilution | 26 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human gastric cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P105655-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or GSTM4 antigen-treated (Neutralization experiment) using P105655(GSTM4 Antibody) at dilution 1/80
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