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Specification
| Full name | GRPR rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. |
| Swissprot No | P30550 |
| Gene Accession | NP_005305 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or GRPR antigen-treated (Neutralization experiment) using P102190(GRPR Antibody) at dilution 1/50 |
| WB Positive control | P102190-WB-1-P |
| WB Recommended dilution | 43 kDa |
| IHC predicted cell location | Predicted cell location: Cell membrane |
| IHC positive control | Positive control: Human bladder cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P102190-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissue or GRPR antigen-treated (Neutralization experiment) using P102190(GRPR Antibody) at dilution 1/50
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We also provide express shippping for time-sensitive deliveries.
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