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Sku: P113466-50 μl
Categories: Primary Antibodies

Specification

Full name GPI rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.
Swissprot No P06744
Gene Accession NP_000166
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human gastric cancer or GPI antigen-treated (Neutralization experiment) using P113466(GPI Antibody) at dilution 1/45
WB Positive control P113466-WB-1-P
WB Recommended dilution 63 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P113466-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer or GPI antigen-treated (Neutralization experiment) using P113466(GPI Antibody) at dilution 1/45

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