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Full name | GNRHR rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. |
Swissprot No | P30968 |
Gene Accession | NP_000397 |
WB Predicted band size | |
WB Positive control | P102220-WB-1-P |
WB Recommended dilution | 38 kDa |
IHC predicted cell location | Predicted cell location: Cell membrane |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 50-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P102220-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or GNRHR antigen-treated (Neutralization experiment) using P102220(GNRHR Antibody) at dilution 1/40
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