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Full name | GGCX rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. |
Swissprot No | P38435 |
Gene Accession | BC013979 |
WB Predicted band size | |
WB Positive control | P100866-WB-1-P |
WB Recommended dilution | 88 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 100-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P100866-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or GGCX antigen-treated (Neutralization experiment) using P100866(GGCX Antibody) at dilution 1/80
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