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Full name | FMO5 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. |
Swissprot No | P49326 |
Gene Accession | BC035687 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or FMO5 antigen-treated (Neutralization experiment) using P109061(FMO5 Antibody) at dilution 1/80 |
WB Positive control | P109061-WB-1-P |
WB Recommended dilution | 60 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P109061-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or FMO5 antigen-treated (Neutralization experiment) using P109061(FMO5 Antibody) at dilution 1/80
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