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Sku: P108613-50 μl
Categories: Primary Antibodies

Specification

Full name FLNA rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Swissprot No P21333
Gene Accession NP_001104026
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human brain tissue or FLNA antigen-treated (Neutralization experiment) using P108613(FLNA Antibody) at dilution 1/50
WB Positive control P108613-WB-1-P
WB Recommended dilution 281 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human colon cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P108613-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or FLNA antigen-treated (Neutralization experiment) using P108613(FLNA Antibody) at dilution 1/50

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