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Specification
| Full name | FGFRL1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. |
| Swissprot No | Q8N441 |
| Gene Accession | NP_068742 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or FGFRL1 antigen-treated (Neutralization experiment) using P100840(FGFRL1 Antibody) at dilution 1/40 |
| WB Positive control | P100840-WB-1-P |
| WB Recommended dilution | 55 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm and Nucleus |
| IHC positive control | Positive control: Human colon cancer |
| IHC Recommed dilution | Recommended dilution: 100-300 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P100840-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or FGFRL1 antigen-treated (Neutralization experiment) using P100840(FGFRL1 Antibody) at dilution 1/40
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