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Sku: P112729-50 μl
Categories: Primary Antibodies

Specification

Full name FBXO32 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swissprot No Q969P5
Gene Accession NP_478136
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or FBXO32 antigen-treated (Neutralization experiment) using P112729(FBXO32 Antibody) at dilution 1/20
WB Positive control P112729-WB-1-P
WB Recommended dilution 42 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human prostate cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P112729-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or FBXO32 antigen-treated (Neutralization experiment) using P112729(FBXO32 Antibody) at dilution 1/20

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