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Full name | EWSR1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. |
Swissprot No | Q01844 |
Gene Accession | BC000527 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or EWSR1 antigen-treated (Neutralization experiment) using P112138(EWSR1 Antibody) at dilution 1/70 |
WB Positive control | P112138-WB-1-P |
WB Recommended dilution | 68 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human esophagus cancer |
IHC Recommed dilution | Recommended dilution: 50-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P112138-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or EWSR1 antigen-treated (Neutralization experiment) using P112138(EWSR1 Antibody) at dilution 1/70
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