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Specification
| Full name | EFNB3 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. |
| Swissprot No | Q15768 |
| Gene Accession | NP_001397 |
| WB Predicted band size | |
| WB Positive control | P107292-WB-1-P |
| WB Recommended dilution | 36 kDa |
| IHC predicted cell location | Predicted cell location: Cell membrane |
| IHC positive control | Positive control: Human thyroid cancer |
| IHC Recommed dilution | Recommended dilution: 25-100 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P107292-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or EFNB3 antigen-treated (Neutralization experiment) using P107292(EFNB3 Antibody) at dilution 1/25
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We also provide express shippping for time-sensitive deliveries.
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