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Sku: P100779-50 μl

Specification

Full name DYNLL1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Swissprot No P63167
Gene Accession BC104245
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or DYNLL1 antigen-treated (Neutralization experiment) using P100779(DYNLL1 Antibody) at dilution 1/120
WB Positive control P100779-WB-1-P
WB Recommended dilution 10 kDa
IHC predicted cell location Predicted cell location: Cytoplasm and Nucleus
IHC positive control Positive control: Human colorectal cancer
IHC Recommed dilution Recommended dilution: 100-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P100779-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or DYNLL1 antigen-treated (Neutralization experiment) using P100779(DYNLL1 Antibody) at dilution 1/120

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