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Sku: P290427-50 μl

Specification

Full name DUSP6 rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit monoclonal
Target Background The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
Swissprot No Q16828
Gene Accession 1848
WB Predicted band size
WB Positive control P290427-WB-1-P
WB Recommended dilution 42 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Avoid repeated freeze-thaw cycles.

WB PIC Description

P290427-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid tissue using P290427(DUSP6 Antibody) at dilution 1/50

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

Email contact@biofargo.com if you have any requirements.

 

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