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Specification
| Full name | DRG1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | DRG1 (developmentally regulated GTP binding protein 1), also known as NEDD3 (neural precursor cell expressed developmentally down-regulated protein 3), is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thought to play a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. |
| Swissprot No | Q9Y295 |
| Gene Accession | BC019285 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or DRG1 antigen-treated (Neutralization experiment) using P100786(DRG1 Antibody) at dilution 1/30 |
| WB Positive control | P100786-WB-1-P |
| WB Recommended dilution | 41 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human thyroid cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P100786-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or DRG1 antigen-treated (Neutralization experiment) using P100786(DRG1 Antibody) at dilution 1/30
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