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Full name | DMAP1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. |
Swissprot No | Q9NPF5 |
Gene Accession | EAX07050 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or DMAP1 antigen-treated (Neutralization experiment) using P111281(DMAP1 Antibody) at dilution 1/25 |
WB Positive control | P111281-WB-1-P |
WB Recommended dilution | 53 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm or Nucleus |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 25-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P111281-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or DMAP1 antigen-treated (Neutralization experiment) using P111281(DMAP1 Antibody) at dilution 1/25
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