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Sku: P110227-50 μl

Specification

Full name DIO2 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swissprot No Q92813
Gene Accession NP_000784
WB Predicted band size
WB Positive control P110227-WB-1-P
WB Recommended dilution 31 kDa
IHC predicted cell location
IHC positive control
IHC Recommed dilution

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P110227-WB-1-P

When can I expect my order to ship?

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Our standard shipping usually take 2-5 days.

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