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$35.00
Sku: D0231-500mL
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by August 08, 2026
Description
Laboratory synthesis and solution preparation often require a high-purity solvent capable of handling a broad range of organic and inorganic chemicals. Solvent water content, evaporation residue, acidity, storage conditions, and compatibility with laboratory materials can all affect handling and experimental consistency.
Dimethyl Sulfoxide (DMSO), Catalog No. D0231, is an ACS-grade, highly polar organic reagent supplied with an assay specification of ≥99.9%. It is provided as a clear, colorless liquid and is miscible with water. DMSO is also soluble in ethanol, acetone, ether, benzene, and chloroform.
DMSO is very hygroscopic and should be protected from moisture. Because its melting point is approximately 18.45°C, the product may arrive partially or completely solidified when exposed to cooler temperatures. According to the product information, solidified DMSO can be reliquefied by warming it to room temperature without detriment to the product.
Specifications
| Product Name | Dimethyl Sulfoxide (DMSO) |
| Catalog No. | D0231 |
| SKU | D0231-500mL |
| Size | 500 mL |
| Grade | ACS |
| CAS No. | 67-68-5 |
| Synonyms | DMSO; Methyl sulfoxide; Dimethyl sulphoxide |
| Molecular Formula | C2H6OS |
| Molecular Weight | 78.13 |
| Appearance | Clear, colorless liquid |
| Assay | ≥99.9% |
| Water (Coulometric KF) | ≤0.1% |
| Residue After Evaporation | ≤0.01% |
| Titratable Acid | ≤0.001 meq/g |
| Melting Point | 18.45°C |
| Boiling Point | 189°C |
| Density | 1.1 g/mL |
| Dielectric Constant | 45 |
| Viscosity | 1.1 centipoises at 27°C |
| Storage | Room temperature |
| Intended Use | For laboratory research use only |
Features
- ACS Grade: Documented as an ACS-grade dimethyl sulfoxide laboratory reagent.
- ≥99.9% Assay: Defined purity specification for laboratory solvent and organic synthesis requirements.
- Controlled Water Content: Water specification of ≤0.1% by coulometric Karl Fischer testing.
- Low Evaporation Residue: Residue after evaporation is specified at ≤0.01%.
- Broad Solvent Compatibility: Miscible with water and soluble in several documented organic solvents.
- Documented Material Compatibility: Product information identifies compatible, moderately compatible, and incompatible laboratory materials.
- Room-Temperature Storage: Designed for storage at room temperature while protected from moisture.
Applications
D0231 ACS-grade dimethyl sulfoxide is intended for laboratory research applications requiring DMSO as a highly polar solvent or reaction reagent. Documented applications include:
- Laboratory Solvent: Used for dissolving organic and inorganic chemicals.
- Organic Synthesis: Used as a solvent or reaction reagent in documented organic synthesis processes.
- Thiols and Disulfides: Used in the oxidation of thiols and disulfides to sulfonic acids.
- Epoxide Reactions: Participates in the hydrolysis of epoxides.
- Phenol Reactions: Participates in the thioalkylation of phenols.
- Aldehyde Preparation: Participates in the oxidation of primary alcohols, primary halides, and esters of primary alcohols to aldehydes.
- Laboratory Solution Preparation: Miscible with water and soluble in ethanol, acetone, ether, benzene, and chloroform.
Solubility and Preparation
| Medium or Solvent | Documented Information |
|---|---|
| Water | Miscible; 1 mL DMSO mixed with 1 mL water yields a clear, colorless solution. |
| Ethanol | Soluble |
| Acetone | Soluble |
| Ether | Soluble |
| Benzene | Soluble |
| Chloroform | Soluble |
Filtration guidance: To prepare a sterile-filtered DMSO solution, the product information recommends a Teflon or nylon membrane. Cellulose acetate membranes are not recommended.
Moisture control: DMSO is very hygroscopic. Minimize exposure to ambient moisture and keep the container tightly closed when not in use.
Material Compatibility
| Compatibility | Materials Listed in the Product Information |
|---|---|
| Compatible | LDPE, HDPE, polypropylene, PPCO (polypropylene copolymer), polymethylpentene, nylon, and Teflon FEP |
| Moderately Compatible | Polystyrene and ECTFE/ETFE |
| Incompatible | Polysulfone, flexible PVC tubing, rigid PVC tubing, and polycarbonate |
Material selection should account for the actual concentration, temperature, contact time, and conditions of use.
Storage and Handling
- Store at room temperature.
- Keep the container tightly closed in a dry, well-ventilated location.
- Protect the product from exposure to moisture because DMSO is hygroscopic.
- DMSO may arrive solidified because its melting point is near room temperature.
- Allow solidified product to warm to room temperature until it returns to a liquid state.
- Keep away from heat, hot surfaces, sparks, open flames, and other ignition sources.
- Wear appropriate protective gloves and eye or face protection when handling.
- Consult the Safety Data Sheet before use.
Safety and Use Limitations
The Safety Data Sheet classifies D0231 dimethyl sulfoxide as a Category 4 combustible liquid and identifies the hazard statement H227: Combustible liquid. The SDS also notes that DMSO is rapidly absorbed through the skin.
Use appropriate laboratory controls and personal protective equipment. Avoid inhalation of vapor or mist, prevent skin and eye contact, and keep the material away from ignition sources.
For laboratory research use only. Not for drug, household, human drug, or animal drug use.
Documents
FAQ
What grade and purity is D0231 Dimethyl Sulfoxide?
D0231 is an ACS-grade dimethyl sulfoxide reagent with an assay specification of ≥99.9%.
What is ACS-grade DMSO used for?
D0231 is intended for laboratory research applications requiring DMSO as a solvent or reaction reagent. Documented uses include dissolving organic and inorganic chemicals and participating in several organic synthesis reactions.
Why did the DMSO arrive partially or completely solidified?
DMSO has a melting point near room temperature. The product information lists a melting point of 18.45°C, while the SDS gives a melting range of 16–19°C. Exposure to cooler temperatures can therefore cause the material to solidify.
How should solidified DMSO be reliquefied?
The product information states that solidified DMSO can be reliquefied by warming it to room temperature without detriment to the product.
Is DMSO miscible with water?
Yes. The product information states that D0231 is miscible with water. Mixing 1 mL of DMSO with 1 mL of water yields a clear, colorless solution.
Is DMSO hygroscopic?
Yes. DMSO is very hygroscopic and should be protected from moisture. Keep the container tightly closed in a dry, well-ventilated place.
Which plastics are compatible with DMSO?
The product information lists LDPE, HDPE, polypropylene, PPCO, polymethylpentene, nylon, and Teflon FEP as compatible. Polysulfone, flexible or rigid PVC tubing, and polycarbonate are listed as incompatible.
Which membrane is recommended for filtering a DMSO solution?
The product information recommends Teflon or nylon membranes when preparing a sterile-filtered DMSO solution. Cellulose acetate membranes are not recommended.
Is D0231 designated as cell-culture grade or sterile DMSO?
The available product documents identify D0231 as an ACS-grade laboratory reagent and do not designate the supplied product as cell-culture grade or sterile. The product information separately provides instructions for preparing a sterile-filtered DMSO solution.
Is D0231 intended for human or animal drug use?
No. D0231 is intended for laboratory research use only and is not intended for human or animal drug use.
For laboratory research use only. Not for drug, household, human drug, or animal drug use.
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
