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Sku: P100201-50 μl
Categories: Primary Antibodies

Specification

Full name CYP1A1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Swissprot No P04798
Gene Accession BC023019
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using P100201(CYP1A1 Antibody) at dilution 1/25
WB Positive control P100201-WB-1-P
WB Recommended dilution 58 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 25-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P100201-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P100201(CYP1A1 Antibody) at dilution 1/25

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