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Full name | CTSL rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. |
Swissprot No | P07711 |
Gene Accession | BC012612 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or CTSL antigen-treated (Neutralization experiment) using P100149(CTSL Antibody) at dilution 1/40 |
WB Positive control | P100149-WB-1-P |
WB Recommended dilution | 38 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human brain |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P100149-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human brain tissue or CTSL antigen-treated (Neutralization experiment) using P100149(CTSL Antibody) at dilution 1/40
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