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Sku: P100149-50 μl
Categories: Primary Antibodies

Specification

Full name CTSL rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell.
Swissprot No P07711
Gene Accession BC012612
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or CTSL antigen-treated (Neutralization experiment) using P100149(CTSL Antibody) at dilution 1/40
WB Positive control P100149-WB-1-P
WB Recommended dilution 38 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human brain
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P100149-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human brain tissue or CTSL antigen-treated (Neutralization experiment) using P100149(CTSL Antibody) at dilution 1/40

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