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Sku: P103377-50 μl
Categories: Primary Antibodies

Specification

Full name COX7A2L rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.
Swissprot No O14548
Gene Accession BC007095
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or COX7A2L antigen-treated (Neutralization experiment) using P103377(COX7A2L Antibody) at dilution 1/65
WB Positive control P103377-WB-1-P
WB Recommended dilution 13 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P103377-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or COX7A2L antigen-treated (Neutralization experiment) using P103377(COX7A2L Antibody) at dilution 1/65

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