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Full name | COX4I1 mouse monoclnal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | mouse monoclonal |
Applications | WB, IHC |
Host | Mouse |
Clone type | mouse monoclonal |
Target Background | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Swissprot No | P13073 |
Gene Accession | |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using P113914(COX4I1 Antibody) at dilution 1/300 |
WB Positive control | P113914-WB-1-P |
WB Recommended dilution | 20 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer and Human colorectal cancer |
IHC Recommed dilution | Recommended dilution: 100-500 |
Ascitic fluid with 0.05% sodium azide and 40% glycerol
P113914-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer and Human colorectal cancer tissue using P113914(COX4I1 Antibody) at dilution 1/300
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