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Full name | CLDN6 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
Swissprot No | P56747 |
Gene Accession | NP_067018 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or CLDN6 antigen-treated (Neutralization experiment) using P114844(CLDN6 Antibody) at dilution 1/50 |
WB Positive control | P114844-WB-1-P |
WB Recommended dilution | 23 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P114844-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or CLDN6 antigen-treated (Neutralization experiment) using P114844(CLDN6 Antibody) at dilution 1/50
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