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Full name | CLDN1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. |
Swissprot No | O95832 |
Gene Accession | NP_066924 |
WB Predicted band size | |
WB Positive control | P106141-WB-1-P |
WB Recommended dilution | 23 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm and Cell membrane |
IHC positive control | Positive control: Human esophagus cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P106141-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or CLDN1 antigen-treated (Neutralization experiment) using P106141(CLDN1 Antibody) at dilution 1/50
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