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Sku: P109329-50 μl
Categories: Primary Antibodies

Specification

Full name CHCHD5 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background CHCHD5 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 5) is a 110 amino acid protein that contains one CHCH domain. The gene encoding CHCHD5 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
Swissprot No Q9BSY4
Gene Accession BC004498
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or CHCHD5 antigen-treated (Neutralization experiment) using P109329(CHCHD5 Antibody) at dilution 1/20
WB Positive control P109329-WB-1-P
WB Recommended dilution 12 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human gastric cancer
IHC Recommed dilution Recommended dilution: 20-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P109329-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or CHCHD5 antigen-treated (Neutralization experiment) using P109329(CHCHD5 Antibody) at dilution 1/20

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